1904 NN.

Dmd065755 1891..1904

The cytochrome P450 2C19 (CYP2C19) enzyme plays an important role in the metabolism of many commonly used drugs. Relatively little is known about CYP2C19 inhibitors, including compounds of natural origin, which could inhibit CYP2C19, potentially causing clinically relevant metabolism-based drug interactions. We evaluated a series (N = 49) of structurally related plant isoquinoline alkaloids for...

Op-scan130187 1904..1913

Silvio Ionta,* Roberto Martuzzi, Roy Salomon, and Olaf Blanke Center for Neuroprosthetics, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland; Laboratory of Cognitive Neuroscience, Brain-Mind Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland; and Department of Neurology, University Ho...

Ernst Mayr: 1904 – 2005

One Long Argument, the title of one of Ernst Mayr's later popular books on evolution, in many ways sums up the core of his intellectual life. Mayr, a leading evolutionary biologist over many years of the past century, who died aged 100 last month, was an explorer, naturalist, ornithologist, philosopher, historian of science and Harvard academic. Like Darwin, he was studying medicine when his fo...

Jean Jacques DuMortier 1904-1934

Jean DuMortier from whom he received a rich physical and mental' inheritance. His early education was received in the Norwalk public schools and at Harstrom's Preparatory School. He went to Williams College for two years, where he creditably participated in athletics-swimming, track, and football. His last two years of college were spent at Columbia University where he received the degree of Ba...

Sir George Pickering (1904-1982).